A 23 years old female presented to the ER with a severe central abdominal pain associated with bilious vomiting. There was no significant past medical history, with no surgeries in the past. She is on contraceptive pills which she started recently She does not smoke, and drink alcohol occasionally. Her Father has a history of epilepsy, and her mother is diabetic.
On physical examination she was distressed secondary to severe pain. Afebrile, BP 178/105, HR 122. And RR 16. The abdomen was diffusely very tenderl, and the bowel sounds were present. The rest of the physical exam was normal.
The patient was admitted to the general medical floor and started on Intravenous normal saline, metoclopramide for the vomiting, and morphine for her abdominal pain. Next morning the nurse noticed while she was trying to insert a urinary catheter that the patient has weakness of both lower extremities. and called the intern. The intern noticed that she has left shoulder weakness exam and during the neurological exam she had a grand mal epeliptic seizure and transferred to the intensive care unit.
Laboratory evaluation shows WBC 17X10⁹/l, Hemoglobin 14 g/dl, Platelets 390x 10⁹/l, Sodium 123 meq/L, Potassium 3 meq/L, Chloride 102 meq/L Bicarb 22 meq/L Urea 15 mg/dL, serum Creatinine 1.1 mg/dL, Serum glucose 78 mg/dL Calcium 10 mg/dL, Billirubin 0.9 mg/dL, and AST, ALT 42 U/l, 44 U/L consequently
Her chest x-ray showed no evidence of acute changes. CT of the Brain and Abdomen were both normal
What is the most likely diagnosis?
How would you confirm your diagnosis?
How would you manage this patient?
How would you manage her Seizures?